The mission of this page is to provide web links for medical papers, clinical study results and various articles that have been published on the effects of heat on people with MS and the benefits of cooling. We are making no medical, clinical or any other type of recommendations in regard to this subject. Please consult your health care professional before buying or using any body cooling product.
Excellent Overviews on MS and Cooling:MSAA Multiple Sclerosis and Cooling, 3rd edition
Written by: Adam Roberts and Judith Harper-Bennie
Edited by: Jack Burks, M.D., Andrea Borkowski, Susan Wells Courtney and Neal Zoren
Why MS and Cooling?
A video of Dr. Daniel Kantor at the Consortium of MS Clinics, 2014
Neurology Care; Cooling Therapy
April, 2011 by Dr. Allen C. Bowling, M.D., Ph.D.
Research and Articles by Date:
2014Whole-body cooling does not compromise muscle oxidative capacity in subjects with MS
NeuroRehabilitation 2014 Rehabilitation Research Center (REVAL), Biomed, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium. Heart Centre Hasselt, Jessa Hospital, Hasselt, Belgium.
Body Temp is elevated and linked to fatigue in relapsing remitting MS, even without heat exposure.
Arch Phys Med Rehabil. 2014 July
An Overview of Heat Intolerance and MS
Julie Stachowiak, Ph.D.
Ollie Jay and
Scott Davis (1104.17)
2012MS Symptoms and Heat
March, 2012; Multiple Sclerosis Research, Barts and the London School of Medicine
2011Warm Weather May Cloud Thinking in MS Patients
Kessler Foundation in West Orange, N.J. February, 2011.
AAN: In MS, Memory Melts in Warm Weather, by Crystal Phend, Senior Staff Writer, MedPage Today.
Published: February 17, 2011
Temperature and MS Multiple Sclerosis Society - UK February, 2010
WebMD, Multiple Sclerosis and Exercise March, 2010
Thermoregulation in Multiple Sclerosis November, 2010
Thermoregulation in Multiple Sclerosis.
Davis SL, Wilson TE, White AT, Frohman EM.
J Appl Physiol. 2010 Jul 29. [Epub ahead of print]
2009Peripheral nerves are progressively involved in multiple sclerosis--a hypothesis from a pilot study of temperature sensitized electroneurographic screening.
Hidasi E, Dioszeghy P, Csépany T, Mechler F, Bereczki D.
Med Hypotheses. 2009 May;72(5):562-6. Epub 2009 Jan 19.
2008Cooling via one hand improves physical performance in heat-sensitive individuals with Multiple Sclerosis: A preliminary study
Modeling Uhthoff's phenomenon in MS patients with internuclear ophthalmoparesis.
Davis SL, Frohman TC, Crandall CG, Brown MJ, Mills DA, Kramer PD, Stuve O, Frohman EM. Neurology
. 2008 Mar 25;70(13 Pt 2):1098-106. Epub 2008 Feb 20.
2007Cool Down MS
Valeo, Tom. Neurology Now.
p 40-41, American Academy of Neurology.
Advanced lightweight cooling-garment technology: functional improvements in thermosensitive patients with multiple sclerosis.
Meyer-Heim A, Rothmaier M, Weder M, Kool J, Schenk P, Kesselring J.
. 2007 Mar;13(2):232-7. Epub 2007 Jan 29.
2006Handbook of Multiple Sclerosis
By Stuart D. Cook
Page 289 "Body Cooling" 2006
Evaluation of a single session with cooling garment for persons with multiple sclerosis--a randomized trial.
Nilsagard Y, Denison E, Gunnarsson LG.
Disability and Rehabilitation: Assistive Technology. 2006 Sep;1(4):225-33.
2005Experts Examine Cooling Therapy for MS
John C. Martin, MS Neighborhood, February 2005
Effects of peripheral cooling on intention tremor in multiple sclerosis
P Feys, W Helsen, X Liu, D Mooren, H Albrecht, B Nuttin, P Ketelaer.
Journal of Neurology, Neurosurgery and Psychiatry. 2005 Mar; v.76(3):373-9.
MS and Cooling the Body Before or During Exercise
Medical News Today November, 2005
2004MSAA Brochure "Multiple Sclerosis and Cooling, Third Edition" 2004
2003A randomized controlled study of the acute and chronic effects of cooling therapy for MS.
Schwid SR, Petrie MD, Murray R, Leitch J, Bowen J, Alquist A, Pelligrino R, Roberts A, Harper-Bennie J, Milan MD, Guisado R, Luna B, Montgomery L, Lamparter R, Ku YT, Lee H, Goldwater D, Cutter G, Webbon B; NASA/MS Cooling Study Group. Neurology. 2003 Jun 24;60(12):1955-60.
The cooling-suit: case studies of its influence on fatigue among eight individuals with multiple sclerosis.
Flensner G, Lindencrona C.
Journal of Advanced Nursing
. 2002 Mar;37(6):541-50.
2002Thermal regulatory responses to submaximal cycling following lower-body cooling in humans
Thad E. Wilson, Stephen C. Johnson, Jack H. Petajan
Scott L. Davis, Eduard Gappmaier
Maurie J. Luetkemeier, Andrea T. White
2001Cooling Vest Improves Symptoms for MS Patients
American Academy of Neurology, September 2001
Cooling Vest May Help Ease MS Symptoms
Care Cure Community September, 2001
Cooling Vest Aids MS Symptoms
BBC News September, 2001
Exercise in 94Â°F Water for a Patient with Multiple Sclerosis
Physical Therapy April 2001 col. 81 no. 4 1049-1058
Cooling garment treatment in MS: Clinical improvement and decrease in leukocyte NO production
2000Effect of precooling on physical performance in multiple sclerosis
A T White, T E Wilson, S L Davis, J H Petajan
Mult Scler June 2000 6: 176-180, doi:10.1177/135245850000600307
COOLING SUIT FOR MULTIPLE SCLEROSIS: FUNCTIONAL IMPROVEMENT IN DAILY LIVING?
Department of Neurology, Lnssjukhuset, SE-30185 Halmstad, Sweden March 2000
Physiologic and functional responses of MS patients to body cooling.
Ku YT, Montgomery LD, Lee HC, Luna B, Webbon BW.
American Journal of Physical Medicine and Rehabilitation. 2000 Sep-Oct;79(5):427-34.
Effect of cooling suit treatment in patients with multiple sclerosis evaluated by evoked potentials.
Kinnman J, Andersson T, Andersson G.
Scandinavian Journal of Rehabilitation Medicine. 2000 Mar;32(1):16-9.
Taming the DOG DAYS. (Caring for heat intolerance symptoms)
Smith, David W.E.
Inside MS Magazine. June 22, 2000.
1999Physiologic and thermal responses of male and female patients with multiple sclerosis to head and neck cooling.
Ku YT, Montgomery LD, Wenzel KC, Webbon BW, Burks JS.
Am J Phys Med Rehabil. 1999 Sep-Oct;78(5):447-56.
The cooling-suit: a study of ten multiple sclerosis patients' experiences in daily life.
Flensner G, Lindencrona C.
J Adv Nurs. 1999 Jun;29(6):1444-53. Erratum in: J Adv Nurs 1999 Sep;30(3):775.
1998[Local ice application in therapy of kinetic limb ataxia. Clinical assessment of positive treatment effects in patients with multiple sclerosis]
Albrecht H, Schwecht M, Pollmann W, Parag D, Erasmus LP, Konig N.
Nervenarzt. 1998 Dec;69(12):1066-73. German.
1997Body cooling may not improve somatosensory pathway function in multiple sclerosis.
Robinson LR, Kraft GH, Fitts SS, Schneider V.
Am J Phys Med Rehabil. 1997 May-Jun;76(3):191-6.
Enhancement of Cognitive Processing by Multiple Sclerosis Patients Using Liquid Cooling Technology: A Case Study
Montgomery L.D., Montgomery R.W., and Ku Y.E. Submitted in 1998 for publication to Am. Journal Phys Med Rehabil.
1996Clinical and Immunological Effects of Cooling in Multiple Sclerosis
Department of Neurology, HSC T-12, SUNY at Stony Brook, Stony Brook, NY 11794 1996
Hemodynamic and thermal responses to head and neck cooling in men and women.
Ku YT, Montgomery LD, Webbon BW.
Am J Phys Med Rehabil. 1996 Nov-Dec;75(6):443-50.
1995Quantification of Uhthoff's phenomenon in multiple sclerosis: a magnetic stimulation study
Laryngeal Uhthoff's phenomenon: a case report.
Pringle CE, McEwan LM, Ebers GC.
Mult Scler. 1995 Nov;1(3):163-4.
Lowering body temperature with a cooling suit as symptomatic treatment for thermosensitive multiple sclerosis patients.
Capello E, Gardella M, Leandri M, Abbruzzese G, Minatel C, Tartaglione A, Battaglia M, Mancardi GL.
Ital J Neurol Sci. 1995 Nov;16(8):533-9.
1993Thermal sensitivity in demyelinating neuropathy.
Chaudhry V, Crawford TO, DeRossett SE.
. 1993 Mar;16(3):301-6.
1992Increased visual impairment after exercise (Uhthoff's phenomenon) in multiple sclerosis: therapeutic possibilities.
van Diemen HA, van Dongen MM, Dammers JW, Polman CH.
Eur Neurol. 1992;32(4):231-4.
1983[Effect of exposure to different temperatures on the clinical manifestations of multiple sclerosis]
Zavalishin IA, Nevskaia OM.
Zh Nevropatol Psikhiatr Im S S Korsakova
. 1983;83(2):170-3. Russian.
Persistent neurological deficit precipitated by hot bath test in multiple sclerosis.